Caloric restriction and intermittent fasting have also been shown to straight inhibit the mTOR pathway, thus relieving the inhibition in the autophagy pathway to end in apoptosis. Conversely, intermittent fasting is demonstrated to activate AMPK, which inhibits mTOR from halting autophagy in rapidly increasing cancer cells. Lastly, the ketogenic https://directivepublications.org/world-journal-of-clinical-cancer-research/